Age: 50
Occupation: Actress
Previous TIME 100 appearances: 0
The queen of the indies, as TIME's Richard Corliss has dubbed her, is the brooding art-house actor who has made a thunderous impact on mainstream Hollywood. Regularly lauded as being among the best in her craft, she is equally at home in obscure indies (Orlando) and blockbusters like the Narnia franchise. Last year found her speaking both Italian and Russian in I Am Love.